Map a manual prenatal-diagnostics workflow with more than 40 process steps and define how higher sample volumes could be processed with less manual intervention.
A concept for automated high-volume sample processing using a proposed two-robot architecture for maternal plasma, serum and whole-blood handling.
Concept target: increase proposed processing capacity from 8 to 24 samples per eight-hour shift while reducing manual handling and associated error risk.
Production context, equipment design, scope of delivery and verified customer value.
ARCEDI had developed a non-invasive prenatal diagnostics process based on analysis of cell-free fetal DNA in maternal blood.
The existing laboratory workflow involved more than 40 manual process steps. ARCEDI needed to understand how the process could be automated to support higher sample volumes while reducing manual handling and the associated risk of process errors.
DIS/CREADIS was engaged to map the existing workflow and develop a concept for a future automated sample-processing system.
DIS/CREADIS mapped the existing laboratory process and developed a concept for automated high-volume sample processing.
The proposed system architecture incorporated two robots and was designed around automated handling of maternal plasma, serum and whole-blood samples.
The concept defined how the individual laboratory operations could be brought together into an automated process and how the proposed equipment could support higher sample volumes.
The project ended at concept stage. No production machine was built or commissioned as part of this project.
SCOPE OF DELIVERY
Existing process mapping
Automation opportunity assessment
Concept development
Sample-handling concept
Two-robot architecture
Equipment concept definition
Capacity and workflow evaluation
Concept targets only. These were not measured production results.
Concept development, Laboratory automation concept, Process mapping, Automation opportunity assessment, Sample handling concept, Maternal plasma handling, Serum handling, Whole-blood handling, Robot system concept, Two-robot architecture, Equipment concept definition, Process integration concept, Capacity evaluation, Workflow evaluation
Built by DIS Systems. Backed by DIS/CREADIS.
